Mycophenolate mofetil (CellCept): an alternative therapy for autoimmune inflammatory myopathy
نویسندگان
چکیده
منابع مشابه
Mycophenolate mofetil as an alternative treatment for autoimmune hepatitis
Autoimmune hepatitis (AIH) is an immune-mediated chronic liver disease characterized by hepatocellular inflammation, necrosis, and fibrosis, which can progress to cirrhosis and fulminant hepatic failure. The standard treatment for AIH includes corticosteroids alone or in combination with azathioprine. Although most patients achieve remission using the standard regimen, some patients do not resp...
متن کاملMycophenolate Mofetil Therapy in Refractory Inflammatory Eye Disease.
PURPOSE To study the efficacy and incidence of treatment-related side effects of mycophenolate mofetil (MMF) therapy in patients with noninfectious inflammatory eye diseases. METHODS Retrospective cohort study of 27 Chilean patients treated for noninfectious inflammatory eye diseases using MMF therapy over a 10-year period. Main outcome measures were: ability to control ocular inflammation an...
متن کاملMycophenolate mofetil as therapy for pyoderma gangrenosum.
BACKGROUND Pyoderma gangrenosum is an ulcerative condition that may be associated with inflammatory bowel disease or inflammatory arthritis. In addition to local wound care, management often includes the use of systemic corticosteroids or systemically administered immunomodulatory agents. OBSERVATIONS We retrospectively analyzed 7 patients with pyoderma gangrenosum who were treated with mycop...
متن کاملImmunosuppression of experimental autoimmune myasthenia gravis by mycophenolate mofetil.
Currently used non-specific immunosuppressive drugs often require intervention in myasthenia gravis (MG) and clinical improvement varies widely. To analyze the therapeutic effect of mycophenolate mofetil (MMF) in experimental autoimmune MG (EAMG), rats were immunized with acetylcholine receptors (AChRs) and subsequently treated with MMF or vehicle. MMF treatment resulted in a significant suppre...
متن کاملRole of mycophenolate mofetil in the treatment of autoimmune hepatitis.
More than 30 years ago controlled clinical trials demonstrated that treatment with steroids improves the outcome of patients with autoimmune hepatitis (AIH) decisively. Azathioprine was soon found to add benefit in the therapy of AIH and was shown to be the drug of choice for maintenance therapy. Since then, corticosteroid monotherapy and the combination of steroids with azathioprine have becom...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2005
ISSN: 1460-2172
DOI: 10.1093/rheumatology/keh499